Dr. Diana Messadi spoke with Dr. John O’Keefe about an article she published with her colleagues recently in PLOS One. The article is titled: Characterization of Electronic Cigarette Aerosol and Its Induction of Oxidative Stress Response in Oral Keratinocytes
Read the article here (PDF)
Dr. Diana Messadi is Chair of the Section of Oral Medicine & Orofacial Pain and Associate Dean for Education and Faculty Development at the UCLA School of Dentistry.
Dr. Messadi and her colleague recently published an article which studied the in vitro effect of e-cigarettes on oral tissues. Some of the key findings are noted below.
- Vapour and liquid byproducts of the e-cigarettes, when introduced to tissue cultures, led to a substantial reduction of the enzyme glutathione involved in redox balance reactions
- This reduction induces oxidative stress and a marker for cytotoxicity and carcinogenicity
- This, also, increases inflammation in lung disease and has implications for periodontal disease and oral cancer
- Adolescents are among the highest percentage of first-time users of tobacco products via e-cigarettes. Therefore, it is important to discourage them from starting to use these products as it can be a gateway to using other tobacco products or even, future substance abuse.
- Nowadays, adults are using e-cigarettes as a tobacco cessation method. However, this is not an approved form of tobacco cessation. As a practitioner, we should advise them to use them only for a pre-defined period of time.
- Patients should be advised that e-cigarette vapour contains the same chemical carcinogens including formaldehyde, acetaldehyde, lead, hydrocarbons which are found in traditional cigarettes and tobacco products.