Article from ADA.

• Artificial saliva is a product that is used by people who have too little of their own naturally occurring saliva (a condition known as dry mouth or xerostomia).
• Although artificial saliva is not a perfect substitute for natural saliva (which is very complex physically and chemically), it can—when used regularly and as directed—help moisten the oral tissues and lessen the discomfort caused by dry mouth.
• A company earns the ADA Seal of Acceptance by producing scientific evidence that demonstrates the safety and efficacy of its product, which the ADA Council on Scientific Affairs carefully evaluates according to objective requirements.

Artificial saliva is a product that is used by people who have too little of their own naturally occurring saliva (a condition known as dry mouth). Dry mouth, also called xerostomia, results from an inadequate flow of saliva. Drying irritates the soft tissues in the mouth, which can make them inflamed and more susceptible to infection. Severe dry mouth can promote the growth of harmful organisms. Without the cleansing and shielding effects of adequate saliva flow, tooth decay and periodontal (gum) disease are more likely to occur.

Constant dryness and the lack of protection provided by saliva contribute to bad breath. Dry mouth may also cause full dentures to become less comfortable because there is no thin film of saliva to help them adhere properly to oral tissues. Artificial saliva products are available in various forms, such as aerosols or liquids that are squirted into the mouth.


​Saliva coats and lubricates tissues in the mouth. It helps cleanse the mouth and begins the digestive process as we chew. When the saliva glands do not produce enough saliva, the mouth becomes dry. Although artificial saliva is not a perfect substitute for natural saliva (which is very complex physically and chemically), it can—when used regularly and as directed—help moisten the oral tissues and lessen the discomfort caused by dry mouth. Speaking, chewing and swallowing are made easier when the mouth is moist.

Although more than 99 percent of saliva is water, saliva also contains buffering agents, enzymes and minerals that help keep teeth strong and play a crucial role in maintaining a healthy environment in the mouth. Artificial salivas normally contain a mixture of buffering agents, cellulose derivatives (to increase stickiness and moistening ability) and flavoring agents (such as sorbitol). However, they do not contain the digestive and antibacterial enzymes and other proteins or minerals present in real saliva. Research is underway to try and develop artificial salivas that more closely mimic natural saliva.

Patients may need to ask their pharmacist for the product. Artificial saliva does not require a prescription, but it can be difficult to find on store shelves. It can be used as often as needed. Saliva substitutes are quickly swallowed and, therefore, the moistening and lubricating action has limited duration and repeat applications may be needed. Although saliva substitutes will not cure dry mouth, they can provide temporary relief of some symptoms.


ADA Seal of Acceptance

A company earns the ADA Seal of Acceptance by producing scientific evidence that demonstrates the safety and efficacy of its product. The ADA Council on Scientific Affairs carefully evaluates the evidence according to objective requirements.

• Professional Resources
  
  There are currently no products Accepted in the ADA Seal category of artificial saliva.
  
  
  • ADA Council on Scientific Affairs Report: Managing xerostomia and salivary gland hypofunction--executive summary and full report
  • ADA Oral Health Topics: Aging and Dental Health and Xerostomia (Dry Mouth)
  • ADA Professional Product Review: Palliative Over-the-Counter (OTC) Treatments for Oral Dryness and Inflammation (PDF; pages 21-24)
  
  Patient Resources
  
  
  • JADA “For the Patient” pages:  Managing dry mouth, Oral moisturizers: Products that can help relieve dry mouth, and Sealing the deal: Buying products that have the ADA Seal of Acceptance
  • ADA MouthHealthy: Dry Mouth, Dry Mouth Quiz, Medications and Oral Health, and Saliva
  
  
  

Prepared by: Center for Scientific Information, ADA Science Institute
DisclaimerContent on ADA.org is for informational purposes only, is neither intended to and does not establish a standard of care, and is not a substitute for professional judgment, advice, diagnosis, or treatment. ADA is not responsible for information on external websites linked to this website.

Article from American Dental Association

Facts About Fluoride
Cavities used to be a fact of life. But over the past few decades, tooth decay has been reduced dramatically. The key reason: fluoride. Research has shown that fluoride reduces cavities in both children and adults. It also helps repair the early stages of tooth decay even before the decay becomes visible. Unfortunately, many people continue to be misinformed about fluoride and fluoridation. Fluoride is like any other nutrient; it is safe and effective when used appropriately. This article will help you learn more about the important oral health benefits of fluoride.

• Fluoride: Nature's Cavity Fighter
• Topical Fluorides
• Systemic Fluorides
• Conclusion
• Fluoride Supplement Dosage Schedule—2010

Fluoride: Nature's Cavity Fighter
Fluoride is a mineral that occurs naturally in all water sources, even the oceans. The fluoride ion comes from the element fluorine. Fluorine, the 17th most abundant element in the earth's crust, is never encountered in its free state in nature. It exists only in combination with other elements as a fluoride compound.


Fluoride is effective in preventing and reversing the early signs of dental caries (tooth decay). Researchers have shown that there are several ways through which fluoride achieves its decay-preventive effects. It makes the tooth structure stronger, so teeth are more resistant to acid attacks. Acid is formed when the bacteria in plaque break down sugars and carbohydrates from the diet. Repeated acid attacks break down the tooth, which causes cavities. Fluoride also acts to repair, or remineralize, areas in which acid attacks have already begun. The remineralization effect of fluoride is important because it reverses the early decay process as well as creating a tooth surface that is more resistant to decay.

Fluoride is obtained in two forms: topical and systemic. Topical fluorides strengthen teeth already present in the mouth making them more decay-resistant. Topical fluorides include toothpastes, mouthrinses and professionally applied fluoride therapies.

Systemic fluorides are those that are ingested into the body and become incorporated into forming tooth structures. Systemic fluorides can also give topical protection because fluoride is present in saliva, which continually bathes the teeth. Systemic fluorides include water fluoridation or dietary fluoride supplements in the form of tablets, drops or lozenges.


Sources of fluoride

Community water fluoridation is an extremely effective and inexpensive means of obtaining the fluoride necessary to prevent tooth decay. Studies prove that water fluoridation continues to be effective in reducing tooth decay by at least 25 percent in children and adults, even in the era of widespread availability of fluoride from other sources, such as fluoride toothpaste.
Leading health organizations, including the American Dental Association, the U.S. Centers for Disease Control and Prevention and the American Academy of Pediatric Dentistry support community water fluoridation based on the overwhelming weight of scientific evidence, which continues to establish that it is safe and effective. Water fluoridation reduces tooth decay in both children and adults.

How much fluoride is in your water?
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If your water comes from a public or community water supply, contact the local water supplier to determine the fluoride level. You can also check your local, county or state health department.
There are two Internet sites that also supply information. One is the U.S. Environmental Protection Agency's web (EPA) site for water quality reports (called Consumer Confidence Reports). Another is the U.S. Centers for Disease Control and Prevention's (CDC) fluoridation Website, "My Water's Fluoride." For those states that have provided information to the CDC, the agency's Website lists fluoridation status by water system.
If your water source is a private well, it will need to be tested and the results obtained from a certified laboratory. Contact your local or state health department for information about where you can have a water sample tested.

Water Quality Reports
In 1999, the U.S. Environmental Protection Agency (EPA) began requiring water suppliers to put annual drinking water quality reports into the hands of their customers. Water Quality Reports, (or Consumer Confidence Reports—CCRs) typically may be mailed to your home, placed in the local newspaper or made available through the Internet around July 1 each year. To obtain a copy of the report, contact your local water supplier. The name of the water system (often not the name of the city) can be found on your water bill. If the name of the system is unknown, contact the local health department.

Although the EPA does not have the authority to regulate private drinking water wells, the agency recommends that private well water be tested every year. And although the EPA does not specifically recommend testing private wells for fluoride levels, health professionals will need this information before consideration of prescription of dietary fluoride supplements or to counsel patients about alternative water sources to reduce the risk of fluorosis if the fluoride levels are above 2ppm.

The ADA offers a comprehensive, well-researched publication, Fluoridation Facts that contains answers to frequently asked questions regarding community water fluoridation.

Answers to the questions in Fluoridation Facts are based on generally accepted, peer-reviewed, scientific evidence. They are offered to assist policy makers and the general public in making informed decisions. The answers are supported by thousands of credible scientific articles, which include more than 350 references.

As a result of the widespread availability of these various sources of fluoride, the decay rates in both the U.S. and other countries have greatly diminished.

The proper mix is key
It is important to note that the effective prevention of dental decay requires that the proper mix of both forms of fluoride (topical and systemic) be made available to individuals. Your dentist can help you assess whether you are receiving adequate levels of fluoride for all family members from the two forms (topical and systemic).

Topical Fluorides

Self-Applied
One method of self-applied topical fluoride that is responsible for a significant drop in the level of cavities since 1960 is use of a fluoride-containing toothpaste. The American Dental Association recommends use of a fluoride toothpaste displaying the ADA Seal of Acceptance.

For children younger than 3 years, parents and caregivers should begin brushing children’s teeth as soon as they begin to come into the mouth by using fluoride toothpaste in an amount no more than a smear or the size of a grain of rice. For children 3 to 6 years of age, parents and caregivers should dispense no more than a pea-sized amount of fluoride toothpaste.

Teeth should be brushed thoroughly twice a day (morning and night) or as directed by a dentist or physician. Children’s brushing should be supervised to ensure that they use the appropriate amount of toothpaste. Other sources of self-applied fluoride are mouthrinses designed to be rinsed and spit out, either prescribed by your dentist or an over-the-counter variety. The ADA recommends the use of fluoride mouthrinses, but not for children under six years of age because they may swallow the rinse.

Professionally-Applied
Professionally-applied fluorides are in the form of a gel, foam or rinse, and are applied by a dentist or dental hygienist during dental visits. These fluorides are more concentrated than the self-applied fluorides, and therefore are not needed as frequently. The ADA recommends that dental professionals use any of the professional strength, tray-applied gels or foam products carrying the ADA Seal of Acceptance.
Systemic FluoridesSystemic fluorides such as community water fluoridation and dietary fluoride supplements are effective in reducing tooth decay. These fluorides provide topical as well as systemic protection because fluoride is present in the saliva.

Community Water Fluoridation
Fluoride is present naturally in all water sources. Community water fluoridation, which has been around for 70 years, is simply the process of adjusting the fluoride content of fluoride-deficient water to the recommended level for optimal dental health. That recommended level is 0.7 parts fluoride per million parts water. Water fluoridation has been proven to reduce decay in both children and adults. While water fluoridation is an extremely effective and inexpensive means of obtaining the fluoride necessary for optimal tooth decay prevention, not everyone lives in a community with a centralized, public or private water source that can be fluoridated. For those individuals, fluoride is available in other forms.

Dietary Fluoride Supplements

Dietary fluoride supplements (tablets, drops or lozenges) are available only by prescription and are intended for use by children ages six months to 16 years living in nonfluoridated areas and at high risk of developing tooth decay. Your dentist or physician can prescribe the correct dosage. It is based on the natural fluoride concentration of the child's drinking water and the age of the child (see chart). For optimum benefits, use of dietary fluoride supplements should begin when a child is six months old and be continued daily until the child is 16 years old. The need for taking dietary fluoride supplements over an extended period of time makes dietary fluoride supplements less cost-effective than water fluoridation; therefore, dietary fluoride supplements are considerably less practical as a wide-spread alternative to water fluoridation as a public health measure. Fluoride supplements are recommended only for children living in non-fluoridated areas and at high risk of developing tooth decay.

It is important to note that fluoridated water may be consumed from sources other than the home water supply, such as the workplace, school and/or day care, bottled water, filtered water and from processed beverages and foods prepared with fluoridated water. For this reason, dietary fluoride supplements should be prescribed by carefully following the recommended dosage schedule (see chart). Dietary fluoride supplements are not recommended for children residing in a fluoridated community.

ADA’s Dietary Fluoride Supplement Guidelines Unchanged
The ADA’s dietary fluoride supplement recommendations remain unchanged in light of the new guidelines for community water fluoridation in the U.S. released in April 2015 by the U.S. Public Health Service. The recommendation for fluoride levels in drinking water is newly calibrated at 0.7 milligrams of fluoride per liter of water. The new recommendation, which was supported by the ADA, does not change the ADA Council on Scientific Affairs’ systematic review and clinical recommendation for the use of dietary fluoride supplements that was released in 2010.

ConclusionNo matter how you get the fluoride you need—whether it be through your drinking water, supplements, toothpaste, mouthrinse or professionally applied fluoride—you can be confident that fluoride is silently at work fighting decay. Safe, convenient, effective however you describe it, fluoride fits naturally into any dental care program. For more information about the oral health benefits of fluoride, just ask your dentist

Important Considerations When Using Dosage Schedule:

• If fluoride level is unknown, drinking water should be tested for fluoride content before supplements are prescribed. For testing of fluoride content, contact the local or state health department.
• All sources of fluoride should be evaluated with a thorough fluoride history.
• Patient exposure to multiple water sources can make proper prescribing complex.
• Ingestion of higher than recommended levels of fluoride by children has been associated with an increase in mild dental fluorosis in developing, unerupted teeth.
• Fluoride supplements require long-term compliance on a daily basis.

Additional Resources
​Fluoride and Fluoridation

Article Accessed from Oral B.
​
A good oral-care routine can empower you to show off your healthy smile with confidence. Here are a few tips to help keep your whole mouth free of cavities and tooth decay. And don’t forget that regular checkups can let your dental professional monitor and minimize the risks of decay and cavities by detecting them early on.

The Basics Are Best

In the fight against cavities, following a good daily oral-care regimen is the best course of action. It’s worth noting that decay might be reversible with a regular oral hygiene routine utilizing fluoride toothpaste. Including power brush can help you maximize removal of sticky plaque and food debris. Enamel can repair itself by using minerals from saliva and fluoride from toothpaste or other sources.1 An anti-cavity fluoride toothpaste and electric toothbrush are powerful tools for getting the most out of your routine.

1. Find the right toothbrush for you. Oral-B® Electric Toothbrushes have perfect options for everyone from teens to adults.
2. Brush for two minutes twice a day. Spend at least 30 seconds on each quadrant of your mouth.
3. Use a fluoride toothpaste and rinse. Fluoride has been proven to enhance dental health.
4. Don’t forget to floss. Remove food particles and plaque that brushing may miss.

Want to Do Even More?

A few simple lifestyle adjustments can have big payoffs for your dental health.
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1. Monitor what you eat. Reducing decay depends on a well-balanced diet. Think twice about high-sugar or heavy-starch diets.
2. Get your greens. Dark, leafy fruits and vegetables add calcium and reduce acids in saliva.
3. Stay hydrated. A dry mouth allows plaque to be retained in the mouth. Drink plenty of tap water that contains fluoride.
4. Watch coffee, soda, and alcohol intake. Ingredients in certain liquids and foods discolor the tooth surface, and too much phosphorus depletes calcium.
5. Take supplements. Vitamins C and D help support tooth health. Check with your physician before taking any supplements.

How Can My Dental Professional Help?Visit your dental professionals for a checkup twice a year. Having a professional cleaning and polishing not only keeps your smile bright, but is also an opportunity to have stubborn plaque and tartar removed. A thorough visual exam will reveal small issues before they develop into bigger ones, and X-rays show potential problems that the naked eye can’t detect. And don’t forget—your dental professional is also a great source of advice about the best oral-care products for you.


1 NIH.gov